Human Subject with Unexpected Biodistribution of [ 11 C ] PK 11195

نویسندگان

  • Anne Roivainen
  • Kjell Någren
  • Jere Virta
  • Juha Rinne
چکیده

[N-Methyl11 C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinoline carboxamide [ 11 C]PK11195 is a widely used radiopharmaceutical for in vivo assessment of translocator protein 18 kDa (TSPO) activity using positron emission tomography. Here we present an interesting case of unusual distribution of [ 11 C]PK11195, that is a lack of uptake in tissues known for high expression of the TSPO.

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تاریخ انتشار 2011